Publication details

Method of detoxication of yperite by using haloalkane dehalogenases

Authors

PROKOP Zbyněk DAMBORSKÝ Jiří OPLUŠTIL František FOŘTOVÁ Andrea NAGATA Yuji

Year of publication 2009
Type Patent
MU Faculty or unit

Faculty of Science

Publisher Patentový úřad Ruska
State Russian Federation
Patent's number RU 11311
Description Patent granted in Russia "Method of detoxication of yperite by using haloalkane dehalogenases".The method of detoxification of yperite by the use of haloalkane dehalogenases or their compositions, the method of preparation of dehalogenationating enzymes and of decontamination compositions which contain at least one wild type and/or modified haloalkane dehalogenase (EC 3.8.1.5) as an chemically active component. The preferred dehalogenases are DhaA from Rhodococcus rhodochrous NCIMB 13064, DmbA from Mycobacterium bovis 5033/66 or LinB from Sphingomonas paucimobilis UT26. Decontamination is utilized for detoxification of yperite from the surfaces of instrumentality, constructional objects, the people’s or animal’s skin and elements of environment, when yperite is exposed to the action of decontamination composition at +10 C to +70 C, preferably at +40 C and pH = 4 to 12.
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