Publication details

Detection of metastatic spread to lymph nodes in primary tumors of colorectal cancer patients by analysis of microRNA expression profiles.

Authors

SLABÝ Ondřej FALTEJSKOVÁ Petra SVOBODA Marek HÉŽOVÁ Renata RADOVÁ Lenka ŠÁNA Jiří VYZULA Rostislav

Year of publication 2011
Type Conference abstract
Citation
Description The aim of this study was molecular characterization of primary tumors of colon and rectum using modern and progressive analysis based on expression profiles of 667 microRNAs by quantitative real-time PCR arrays. We analyzed expression profiles of 20 patients without lymph node positivity and 25 patients with lymph node positivity to identify miRNA differentially expressed between these two groups that would alow us to diagnose presence of lymph nodes metastases directly from the primary tumor.

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