Method of Production of Optically Active Hydrocarbons and Alcohols Using Hydrolytic Dehalogenation Catalysed by Haloalkane Dehalogenases.

• Authors: PROKOP Zbyněk; DAMBORSKÝ Jiří; NAGATA Yuji; JANSSEN D. B.
• Year of publication: 2009
• Type: Patent
• MU Faculty or unit: Faculty of Science
• Publisher: USTPO Úřad pro patenty a ochranné známky USA
• State: United States of America
• Patent's number: US 7,632,666
• Description: This invention relates to method for production of optically active haloalkanes, haloalcohols, alcohols, halopolyols and polyols by hydrolytic dehalogenation catalysed by the enzymes haloalkane dehalogenases (Enzyme Commission number EC 3.8.1.5) isolated from microorganisms or altered haloalkane dehalogenases with improved substrate specificity, stereo- or regio-selectivity.

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