Publication details
Extended consensus on need and means to detect vascular variability disorders (VVDs) and vascular variability syndromes (VVSs)
| Authors | |
|---|---|
| Year of publication | 2009 |
| Type | Article in Periodical |
| Magazine / Source | World Heart Journal |
| MU Faculty or unit | |
| Citation | |
| Field | Other specializations of internal medicine |
| Keywords | BIOCOS; MESOR; MESOR-normotension; MESOR-hypertension; excessive pulse pressure; deficient heart rate variability; blood pressure ecphasia; outcome |
| Description | Given that conventional health care practice is concerned mainly with high blood pressure (BP), and given the fact that other variability disorders -- circadian overswing, excessive pulse pressure, odd circadian BP timing and deficient heart rate (HR) variability (in their own right or in combination with MESOR-hypertension) -- are not diagnosed but contribute to cardiovascular disease risk, we wanted to find out 1. how many patients escape current diagnosis (and treatment), and 2. what are the risks such patients incur. A first available database consists of 297 patients (121 normotensives and 176 treated hypertensives). Each condition was considered separately, except that in the case of an excessive pulse pressure, all had also a high BP. In each case, the number of patients who have one, two, three or all four conditions (vascular variability disorders, VVDs) was counted. Their risk was assessed as the percentage incidence of morbid events (cerebral ischemic event, coronary artery disease, nephropathy, retinopathy) that occurred during the 6 years following the BP monitoring (used to diagnose the VVDs). Subjects had no history of morbidity at the time of monitoring. |
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