Ing. RNDr. Martin Marek, Ph.D., MBA
Head, Structural Biology
Correspondence Address:
Kotlářská 267/2, 611 37 Brno
Office: bldg. C13/308
Kamenice 753/5
625 00 Brno
Phone: | +420 549 49 8763 |
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E‑mail: |
Total number of publications: 27
2023
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Advancing Enzyme's Stability and Catalytic Efficiency through Synergy of Force-Field Calculations, Evolutionary Analysis, and Machine Learning
ACS Catalysis, year: 2023, volume: 13, edition: 19, DOI
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Catalytic mechanism for Renilla-type luciferases
Nature Catalysis, year: 2023, volume: 6, edition: 1, DOI
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Deciphering Enzyme Mechanisms with Engineered Ancestors and Substrate Analogues
ChemCatChem, year: 2023, volume: 15, edition: 19, DOI
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Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate
Molecular Neurodegeneration, year: 2023, volume: 18, edition: 1, DOI
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In cellulo and in vivo assays for compound testing cruzi
STAR Protocols, year: 2023, volume: 4, edition: 1, DOI
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Multimeric structure of a subfamily III haloalkane dehalogenase-like enzyme solved by combination of cryo-EM and x-ray crystallography
Protein Science, year: 2023, volume: 32, edition: 10, DOI
2022
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Computer-aided engineering of staphylokinase toward enhanced affinity and selectivity for plasmin
Computational and Structural Biotechnology Journal, year: 2022, volume: 20, edition: May 2022, DOI
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Extended Mechanism of the Plasminogen Activator Staphylokinase Revealed by Global Kinetic Analysis: 1000-fold Higher Catalytic Activity than That of Clinically Used Alteplase
ACS Catalysis, year: 2022, volume: 12, edition: 7, DOI
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Hidden Potential of Highly Efficient and Widely Accessible Thrombolytic Staphylokinase
Stroke, year: 2022, volume: 53, edition: 10, DOI
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Increased occurrence of Treponema spp. and double-species infections in patients with Alzheimer's disease
Science of the Total Environment, year: 2022, volume: 844, edition: October 2022, DOI