Ing. RNDr. Martin Marek, Ph.D., MBA

2022

• Mechanism-Based Strategy for Optimizing HaloTag Protein Labeling

  MARQUES Sérgio Manuel SLÁNSKÁ Michaela CHMELOVÁ Klaudia CHALOUPKOVÁ Radka MAREK Martin CLARK Spencer DAMBORSKÝ Jiří KOOL Eric T. BEDNÁŘ David PROKOP Zbyněk

  Article in Periodical

  JACS AU, year: 2022, volume: 2, edition: 6, DOI

2021

• Computational enzyme design for metabolic engineering

  DAMBORSKÝ Jiří BEDNÁŘ David PROKOP Zbyněk MAREK Martin MAZURENKO Stanislav ŠTOURAČ Jan MARQUES Sérgio Manuel FONSECA PINTO Gabriela Filipa PLANAS IGLESIAS Joan MUSIL Miloš HON Jiří VÁVRA Ondřej KHAN Rayyan Tariq FILIPOVIČ Jiří KOZLÍKOVÁ Barbora

  Conference abstract

  Year: 2021, type: Conference abstract

• Computational Enzyme Stabilization Can Affect Folding Energy Landscapes and Lead to Catalytically Enhanced Domain-Swapped Dimers

  MARKOVÁ Klára KUNKA Antonín CHMELOVÁ Klaudia HAVLÁSEK Martin BABKOVÁ Petra MARQUES Sérgio Manuel VAŠINA Michal PLANAS IGLESIAS Joan CHALOUPKOVÁ Radka BEDNÁŘ David PROKOP Zbyněk DAMBORSKÝ Jiří MAREK Martin

  Article in Periodical

  ACS Catalysis, year: 2021, volume: 11, edition: 21, DOI

• Designované a syntetizované geny kódující nově zkonstruované proteinové katalyzátory (luciferázy) s ověřenými vlastnostmi

  MAREK Martin DAMBORSKÝ Jiří BEDNÁŘ David PLUSKAL Daniel MAJEROVÁ Marika PLANAS IGLESIAS Joan

  Outcomes put into operation (prototype, working sample)

  Year: 2021

• Engineering protein dynamics for the understanding of divergent evolution of the Renilla luciferase

  TOUL Martin SMITH Andrea RANGEL PAMPLONA PIZARRO PINTO José Gaspar MAREK Martin HERNYCHOVÁ Lenka LIŠKOVÁ Veronika PLUSKAL Daniel EMOND Stephane DÖRR Mark PLANAS IGLESIAS Joan CHALOUPKOVÁ Radka BEDNÁŘ David PROKOP Zbyněk BORNSCHEUER Uwe T. HOLLFELDER Florian DAMBORSKÝ Jiří

  Conference abstract

  Year: 2021, type: Conference abstract

• Engineering the protein dynamics of an ancestral luciferase

  SCHENKMAYEROVÁ Andrea RANGEL PAMPLONA PIZARRO PINTO José Gaspar TOUL Martin MAREK Martin HERNYCHOVÁ Lenka PLANAS IGLESIAS Joan LIŠKOVÁ Veronika PLUSKAL Daniel VAŠINA Michal EMOND Stephane DÖRR Mark CHALOUPKOVÁ Radka BEDNÁŘ David PROKOP Zbyněk HOLLFELDER Florian BORNSCHEUER Uwe T. DAMBORSKÝ Jiří

  Article in Periodical

  Nature Communications, year: 2021, volume: 12, edition: 1, DOI

• Species-selective targeting of pathogens revealed by the atypical structure and active site of Trypanosoma cruzi histone deacetylase DAC2

  MAREK Martin RAMOS-MORALES E. PICCHI-CONSTANTE G.F.A. BAYER T. NORSTROM C. HERP D. SALES P.A. GUERRA-SLOMPO E.P. HAUSMANN K. CHAKRABARTI A. SHAIK T.B. MERZ A. TROESCH E. SCHMIDTKUNZ K. GOLDENBERG S. PIERCE R.J. MOURAO MM JUNG M.M. SCHULTZ J. SIPPL W. ZANCHIN N.I.T. ROMIER C.

  Article in Periodical

  Cell Reports, year: 2021, volume: 37, edition: 12, DOI

• The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination

  RAMOS-MORALES Elizabeth BAYAM Efil DEL-POZO-RODRIGUEZ Jordi SALINAS-GIEGE Thalia MAREK Martin TILLY Ramos-Morales, E (Ramos- WOLFF Philippe TROESCH Edouard ENNIFAR Eric DROUARD Laurence GODIN Juliette D. ROMIER Christophe

  Article in Periodical

  Nucleic acids research, year: 2021, volume: 49, edition: 11, DOI

2020

• Decoding the intricate network of molecular interactions of a hyperstable engineered biocatalyst

  MARKOVÁ Klára CHMELOVÁ Klaudia MARQUES Sérgio Manuel CARPENTIER Philippe BEDNÁŘ David DAMBORSKÝ Jiří MAREK Martin

  Article in Periodical

  Chemical Science, year: 2020, volume: 11, edition: 41, DOI

• Structural and catalytic effects of surface loop-helix transplantation within haloalkane dehalogenase family

  MAREK Martin CHALOUPKOVÁ Radka PRUDNIKOVA Tanyana SATO Yukari REZACOVA Pavlina NAGATA Yuji SMATANOVA KUTA Ivana DAMBORSKÝ Jiří

  Article in Periodical

  Computational and Structural Biotechnology Journal, year: 2020, volume: 18, edition: December 2020, DOI