Project information
Project information
The expression of basic fibroblast growth factor (FGF-2) and FGF-receptors in human leukemic cells. Potential use for the monitoring of cancer therapy
- Project Identification
- GA312/97/0393
- Project Period
- 1/1997 - 1/1999
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Standard Projects
- MU Faculty or unit
-
Faculty of Medicine
- Cooperating Organization
-
Institute of Animal Physiology and Genetics of thr ASCR, v. v. i.
- Responsible person prof. Ing. Petr Dvořák, CSc.
- Responsible person Ing. Dana Dvořáková, CSc.
The main objective of this project is to investigate the expression of FGF-2 and FGFR in peripheral blood and the level of secreted FGF-2 in blood and urine of patients with selected with selected lymphoid and myeloid leukemias as a potential monitor of cancer therapy. The results will be correlated with the stage of disease and the underwent treatment. A complementary scientific objectives are to characterize the carbohydrate composition in leukemic cells and to probe the possibility to regulate in vit