Project information
Study the effectiveness of anticancer drugs
(STEAD)
- Project Identification
- MUNI/R/1568/2020
- Project Period
- 1/2021 - 12/2022
- Investor / Pogramme / Project type
-
Masaryk University
- Grant Agency of Masaryk University
- CAREER RESTART
- MU Faculty or unit
- Faculty of Pharmacy
This project is focused on imaging of elements/metals/proteins in biological tissues by a unique method - laser ablation with inductively coupled plasma and mass spectrometry (LA-ICP-MS) after anticancer drug treatment.
In the last decades increased interest in imaging of these elements/metals/proteins distribution, mainly in pharmaceutical, biomedicine research, or life science with application to specific problem/disease. The effectiveness of treatment concerning e.g. targeted release will be investigated by the determination and imaging of the amount of metals from metal-based drugs and proteins in tumor tissues.
Publications
Total number of publications: 6
2023
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ELEMENTS AND PROTEINS IMAGING BY LA-ICP-MS: MEDICAL AND PHARMACEUTICAL RESEARCH
Year: 2023, type:
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Laser Ablation Inductively Coupled Plasma Mass Spectrometry as a Powerful Tool for Spatially Resolved Analysis: An Experiment for Undergraduate Analytical Chemistry Laboratory
Journal of Chemical Education, year: 2023, volume: 100, edition: 5, DOI
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NANO-SAVERS, POTENTIAL THERANOSTICS FOR STROKE DETECTION AND TREATMENT: INVESTIGATION OF THEIR PHARMACOKINETICS
Year: 2023, type: Appeared in Conference without Proceedings
2022
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BIOIMAGING OF ELEMENTS AND PROTEINS BY LA-ICP-MS IN MEDICINE AND PHARMACEUTICAL RESEARCH
Year: 2022, type: Appeared in Conference without Proceedings
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IMAGING OF ELEMENTS AND PROTEINS IN BIOLOGICAL TISSUES: MEDICAL AND PHARMACEUTICAL APPLICATIONS
Year: 2022, type: Appeared in Conference without Proceedings
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Laser ablation imaging in bioapplications
Year: 2022, type: