Bioanalytical quality control of cGMP/ATMP-grade stem cells and progenitors
- Project Identification
- Project Period
- 1/2022 - 12/2023
- Investor / Pogramme / Project type
- Masaryk University
- MU Faculty or unit
- Faculty of Medicine
Stem cells and progenitors represent a core resource for development of advanced therapy medicinal products (ATMPs) for cell therapy and tissue engineering. Safe production of high-quality stem cells and their products for ATMPs strongly depends on stringent culture conditions, following Current Good Manufacturing Practice (cGMP) regulations. In this project we aim to translate the so far experimental quality control (QC) procedures based on mass spectrometry and advanced statistics into standard operation protocols that allow reaching the cGMP and ATMP grades for QC in cultures of stem cells and progenitors.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Total number of publications: 13