Project information
CIISB - Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Project Identification
- LM2023042
- Project Period
- 1/2023 - 12/2026
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
- Central European Institute of Technology
- Project Website
- https://www.ciisb.org/
- Cooperating Organization
-
Institute of Biotechnology CAS
- Responsible person Ing. Jan Dohnálek, PhD.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed national infrastructure, which consists of two nodes, one represented by CEITEC (Central European Institute of Technology, Brno) and second by BIOCEV (Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University, Vestec near Prague). CIISB offers access to 10 core facilities; five of them are part of the Centre of Structural Biology and one of the Mendel Centre of Genomics and Proteomics of Plants of CEITEC Masaryk University and four of the Centre of Molecular Structure of the Institute of Biotechnology AS CR in the BIOCEV Centre.
All CIISB core facilities are in the full operational phase. Projects as OP RDI (Start-up) supported the construction phase, and the built capacities were made available by both CIISB nodes in the form of Open Access to internal and external users. In its construction phase, CIISB (2011-2015) was the Associated National Center of the pan-European research infrastructure INSTRUCT. In 2016, following the completion, putting into operation, and subsequent international evaluation, CIISB became a fully-fledged Instruct-CZ Centre for this distributed infrastructure.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 150
2026
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Anemia-associated mutations disrupt the CDIN1-Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA-I) disease
FEBS Journal, year: 2026, volume: 2026, DOI
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Creatine kinase B, a downstream effector of c-Myb, controls migration of osteosarcoma cells via regulation of N-cadherin
Cancer Cell International, year: 2026, volume: 26, edition: 1, DOI
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Cryo-EM structure of photosystem II supercomplex from a green microalga with extreme phototolerance
Nature communications, year: 2026, volume: 17, edition: 341, DOI
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Genomic and taxonomic characterization of strain CCM 2573: Uncovering unique genetic features and description of Macrococcus caseolyticus subsp. lactis subsp. nov.
FOLIA MICROBIOLOGICA, year: 2026, DOI
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Proteomic Analysis Reveals Accompanying Anion‐Dependent Changes of Cadmium Toxicity During Arabidopsis thaliana Development
PLANT CELL AND ENVIRONMENT, year: 2026, DOI
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Psychrotolerant Erwinia psychrophila sp. nov. and Erwinia magellanica sp. nov. Isolated from Penguin Faeces
CURRENT MICROBIOLOGY, year: 2026, volume: 83, edition: 2, DOI
2025
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14-3-3ζ protein prevents formation of GSK3β-phosphorylated Tau protein fibrils
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, year: 2025, volume: 330, edition: November, DOI
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A Bambusuril Receptor Binds Charge Diffuse Anions in Water at Picomolar Concentrations
Angewandte Chemie International Edition, year: 2025, volume: 64, edition: 37, DOI
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A newly developed cobalt(II) complex derived from a thiourea derivative and assessment of its potential bioapplicability against plant root pathogens
JOURNAL OF COORDINATION CHEMISTRY, year: 2025, volume: 78, edition: 22, DOI
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AFM application across the life sciences field and its combination with special techniques
Year: 2025, type: Conference abstract