Publication details

Rational construction of macrocycles consisting of methylene bridged ureas

Authors

YAWER Mirza Arfan NEČAS Marek ŠINDELÁŘ Vladimír

Year of publication 2016
Type Article in Periodical
Magazine / Source Tetrahedron
MU Faculty or unit

Faculty of Science

Citation
Web http://www.sciencedirect.com/science/article/pii/S0040402016302630
Doi http://dx.doi.org/10.1016/j.tet.2016.04.009
Field Organic chemistry
Keywords Macrocycles; Ureas; Triazinanones; Hydrogen bonding; Condensation
Attached files
Description Synthesis of two macrocycles formed by urea functions connected solely by methylene bridges is described. This is the first example of isolated and fully characterized macrocyclic compounds in which NH containing urea units are separated by methylene bridges. X-ray diffractometry revealed formation of multiple intramolecular hydrogen bonds between acidic NH and oxygen atoms of urea within the macrocycles.
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