Publication details

Přehled difuzních gliomů dle WHO klasifikace 2021 1. část - difuzní gliomy dospělého typu

Title in English Diffuse glioma overview based on the 2021 WHO classification part 1 - adult type
Authors

HENDRYCH Michal BARÁK Martin VALEKOVÁ Hana KAZDA Tomáš POSPÍŠIL Petr LAKOMÝ Radek ŠÁNA Jiří JANČÁLEK Radim HERMANOVÁ Markéta

Year of publication 2023
Type Article in Periodical
Magazine / Source CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.prolekare.cz/casopisy/ceska-slovenska-neurologie/2023-6-6/prehled-difuznich-gliomu-dle-who-klasifi-kace-2021-1-cast-difuzni-gliomy-dospeleho-typu-136180
Doi http://dx.doi.org/10.48095/cccsnn2023359
Keywords diffuse glioma; WHO CNS 2021; integrated diagnostics; glioblastoma; astrocytoma; oligodendroglioma
Description Recent findings in the field of molecular-genetic alterations in diffuse gliomas, encompassing both adult and pediatric types, have initiated significant changes in their classification and diagnostics. These changes are presented in the fifth edition of the WHO Classification of Tumors of the Central Nervous System emphasizing a pivotal shift from the conventional categorization of tumors based on morphology to an integrated diagnostic approach, which incorporates characteristic molecular-genetic and epigenetic alterations alongside traditional morphological features. This review presents a summary of the units that are included in the group of diffuse gliomas of the adult type, with an emphasis on diagnostic criteria and grading according to the fifth edition of the WHO Classification of Tumors of the Central Nervous System, published in 2021.
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