Publication details
High-Resolution Imaging of Transient RNA Polymerase II Biomolecular Condensates
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| Year of publication | 2024 |
| Type | Appeared in Conference without Proceedings |
| MU Faculty or unit | |
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| Description | Biomolecular condensates, which assemble in cells to regulate key biological processes, are challenging to study due to their inherently dynamic nature. In this talk, we will present our integrative multi-scale approach, which integrates light microscopy, electron cryomicroscopy, cryotomography, and coarse-grained simulations. Together, these methods reveal new insights into the molecular organization and biogenesis of a model RNA polymerase II condensate, shedding light on its structural complexity. |