Publication details

Cell Nuclei Segmentation Using Star-Shaped Simplex Meshes



Year of publication 2002
Type Article in Proceedings
Conference Biophysics of the Genome and Its Interactions
MU Faculty or unit

Faculty of Informatics

Field Use of computers, robotics and its application
Keywords Cell nuclei segmentation; simplex meshes; deformable models
Description Fast, reliable and precise cell nucleus boundary reconstruction algorithm is needed for automatic measuring of topographical parameters of the large number of cells or cell nuclei. A reconstruction method based on deformation of star-shaped simplex meshes is presented. The method was used for shape reconstruction of cell nuclei of HL-60 cells stained by DAPI (the whole volume of nuclei was visible in the input 3D images) and cell nuclei of HT-29 cells (nuclear envelope, i.e. surface of nucleus boundary, was visualized using Lamin B)
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