Image analysis of the movement of sub-cellular structures

• Authors: MATULA Petr; ONDŘEJ Vladan; KOZUBEK Stanislav
• Year of publication: 2004
• Type: Article in Proceedings
• Conference: Biophysics of the Genome
• MU Faculty or unit: Faculty of Informatics
• Field: Use of computers, robotics and its application
• Keywords: image analysiss
• Description: Analysis of time-lapse series of images of living cells requires automation. This contribution concerns the main features of the software package developed for this purpose in our laboratory. Some improvements of our recently published method for tracking of sub-cellular structures based on graph theory are presented. The behaviour of the method is evaluated on images of centromeric heterochromatin defined by HP1beta-GFP fusion protein. The results show that the method is very well applicable for this type of data.

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