Publication details
Big endotelin,interleukin 6 a funkce pravé komory
| Title in English | Big endothelin, interleukin 6 and right ventricle function |
|---|---|
| Authors | |
| Year of publication | 2005 |
| Type | Article in Periodical |
| Magazine / Source | Vnitřní lékařství |
| MU Faculty or unit | |
| Citation | |
| Field | Cardiovascular diseases incl. cardiosurgery |
| Keywords | Big endothelin; interleukin 6; right ventricle |
| Description | Objective: Big endothelin (BE) and interleukin 6 (IL 6) belong to important active substances, which are related to severity of heart failure. We compared patients with high and low levels of BE and IL 6 in relation to haemodynamics, left (LV) and right ventricle (RV) functions. Population: 155 patients with chronic heart failure, left ventricular ejection fraction (LVEF) below 40 %, NYHA II–IV, mean age 51.8 +- 8.8 years, 129 men, 26 women. 86 patients were diagnosed with ischaemic heart disease (IHD), 69 patients had dilatation cardiomyopathy (DCMP). Conclusion: Big endothelin and interleukin 6 levels are higher in patients who have systolic dysfunction of the left ventricle accompanied with more pronounced disorder of the right ventricle function than in patients who have disorder of the left cardiac ventricle only. |
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