Publication details

Pokles tkáňového kyslíku koreluje i intenzitou apoptózy u modelu fokální mozkové ischemie - neuroprotektivní vliv systémové hypertenze

Title in English The decrease of tissue oxygen cerrelates with the level of apoptosis in a focal ischemia in rat - the neuroprotective role of systemic hypertension
Authors

OTEVŘEL Filip KUCHTÍČKOVÁ Šárka SMRČKA Martin

Year of publication 2006
Type Article in Proceedings
Conference Kuncův memoriál 2006
MU Faculty or unit

Faculty of Medicine

Citation
Field Neurology, neurosurgery, neurosciences
Keywords the decrease of tissue oxygen; systemic hypertension
Description To establish on a suture ischemia-reperfusion model of cerebal ACM ischemia in a rat whether there is a correlation between the decrease of tissue oxygen during ischemia and the development of apoptosis. To establish whether there is some neuroprotective role of systemic hypertension. Hypertension influences both pt02 and number of apoptotic cells in tissue at risk and works as a good neuroprotection. This finding may have also clinical implications for example in aneurysm surgery.
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