Publication details

Je humorální aktivace u srdečního selhání ovlivněna genetickou dispozicí?

Title in English Is humoral activation in heart failure affected by genetic determination?
Authors

ŠPINAROVÁ Lenka ŠPINAR Jindřich VAŠKŮ Anna PÁVKOVÁ GOLDBERGOVÁ Monika LUDKA Ondřej TOMANDL Josef VÍTOVEC Jiří

Year of publication 2007
Type Article in Periodical
Magazine / Source Cor et Vasa
MU Faculty or unit

Faculty of Medicine

Citation
Field Cardiovascular diseases incl. cardiosurgery
Keywords Genetics-humoral activation-heart failure
Description Aim of study: To document an association between the plasma levels of big endothelin and endothelin-1, clinical parameters and the two most frequent polymorphisms (-3A/-4A and G8002A) of the endothelin-1-encoding gene on the one hand and the plasma levels of TNF-alpha, clinical parameters and the gene polymorphisms of TNF-apha -308 A/G, -238 A/G, TNF-beta Ncol, and 3TACE (tumor necrosis factor-alpha-converting enzyme) in patients with chronic heart failure (HF).
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