Publication details

Micro-RNAs miR125b and miR137 are frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer

Authors

SVOBODA Miroslav IZAKOVIČOVÁ HOLLÁ Lydie ŠEFR Roman VRTKOVÁ Irena KOCÁKOVÁ Ilona TICHÝ Boris DVOŘÁK Josef

Year of publication 2008
Type Article in Periodical
Magazine / Source International Journal of Oncology
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords micro-RNA; miR125b; miR137; preoperative chemoradiotherapy; rectal cancer
Description The aim of this study was to test the possible involvement of micro-RNAs in response to standard anticancer treatment. Our results for the first time show that higher induced levels of miR125b and miR137 are associated with worse response to the therapy.
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