Publication details

Haplotype analysis of interleukine 18 (IL-18) gene in Czech patients with allergic asthma

Authors

IZAKOVIČOVÁ HOLLÁ Lydie SCHÜLLER Marcel KINDLOVÁ Dagmar ZNOJIL Vladimír

Year of publication 2008
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description To test a possible role of IL-18 gene polymorphisms in a Czech population, case-control study including 284 patients with allergic asthma and 312 healthy control subjects was performed. Our results indicate that the three promoter polymorphisms in the IL-18 gene act in a cooperative fashion and suggest that IL-18 haplotypes could play a role in the pathogenesis of allergic asthma in a Czech population.
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