Publication details

EFFECT OF BAROREFLEX ON BLOOD PRESSURE VARIABILITY

Authors

HONZÍKOVÁ Klára HRSTKOVÁ Hana ŠŤASTNÁ Jana NOVÁKOVÁ Zuzana HONZÍKOVÁ Nataša FIŠER Bohumil ZÁVODNÁ Eva KRTIČKA Antoín HONZÍK Petr

Year of publication 2008
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description We studied 58 subjects (20-22 years). Systolic and diastolic blood pressures (SBP, DBP) and inter-beat intervals (IBI) were recorded beat-to-beat for 5 min (Finapres). BRS, and BRSf were determined by the spectral method at 0.1 Hz frequency range. To make a comparison of the quantitative effects of BRS and BRSf on SBPv possible, both variables were expressed as multiples of standard deviations: BRSsd = (BRS – mean BRS) / SD of BRS; BRSfsd = (BRSf – mean BRSf) / SD of BRSf. A negative correlation was found between SBPv and BRSsd (r = - 0.33, p<0.05), and between SBPv and BRSfsd (r = - 0.36, p<0.05). The multiple regression analysis showed higher regression coefficient of BRSfsd than of BRSsd (SBPv = 9.43 – 0.0052*IBI + 0.15*BRSsd – 1.85*BRSfsd, F = 2.92, p<0.05). The analysis revealed that the IBI independent index BRSf [mHz/mmHg] is a better indicator for evaluation of the effectivity of baroreflex sensitivity to suppress the SBP variability than the IBI dependent index BRS [ms/mmHg].
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