Randomized study of interferon beta-1a, low-dose azathioprine, and low-dose corticosteroids in multiple sclerosis

• Authors: HAVRDOVA E.; ZIVADINOV R.; KRASENSKY J.; DWYER M.G.; NOVÁKOVÁ I.; DOLEŽAL O.; TICHÁ V.; DUŠEK Ladislav; HOUŽVIČKOVÁ E.; SVOBODNÍK Adam
• Year of publication: 2009
• Type: Article in Periodical
• Magazine / Source: Multiple sclerosis
• MU Faculty or unit: Faculty of Medicine
• Field: Neurology, neurosurgery, neurosciences
• Keywords: multiple sclerosis
• Description: The Avonex-Steroids-Azathioprine study was placebo-controlled trial and evaluated efficacy of IFN beta-1a alone and combined with low-dose AZA alone or low-dose AZA and low-dose corticosteroids as initial therapy. In IFN beta-naive patients with early active RRMS, combination treatment did not show superiority over IFN beta-1a monotherapy.