Randomized study of interferon beta-1a, low-dose azathioprine, and low-dose corticosteroids in multiple sclerosis

• Autoři: HAVRDOVA E.; ZIVADINOV R.; KRASENSKY J.; DWYER M.G.; NOVÁKOVÁ I.; DOLEŽAL O.; TICHÁ V.; DUŠEK Ladislav; HOUŽVIČKOVÁ E.; SVOBODNÍK Adam
• Rok publikování: 2009
• Druh: Článek v odborném periodiku
• Časopis / Zdroj: Multiple sclerosis
• Fakulta / Pracoviště MU: Lékařská fakulta
• Obor: Neurologie, neurochirurgie, neurovědy
• Klíčová slova: multiple sclerosis
• Popis: The Avonex-Steroids-Azathioprine study was placebo-controlled trial and evaluated efficacy of IFN beta-1a alone and combined with low-dose AZA alone or low-dose AZA and low-dose corticosteroids as initial therapy. In IFN beta-naive patients with early active RRMS, combination treatment did not show superiority over IFN beta-1a monotherapy.