Publication details

1H, 13C, and 15N chemical shift assignments of ZCCHC9

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SAŇUDO ARCE Maria JACKO Martin RAMMELT Christiane VAŇÁČOVÁ Štěpánka ŠTEFL Richard

Year of publication 2010
Type Article in Periodical
Magazine / Source Biomolecular NMR Assignments
MU Faculty or unit

Faculty of Science

Field Genetics and molecular biology
Keywords ZCCHC9; Zinc knuckle; CCHC; RNA degradation
Description ZCCHC9 is a human nuclear protein with sequence homology to yeast Air1p/Air2p proteins which are RNA-binding subunits of the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex involved in nuclear RNA quality control and degradation in yeast. The ZCCHC9 protein contains four retroviral-type zinc knuckle motifs. Here, we report the NMR spectral assignment of the zinc knuckle region of ZCCHC9. These data will allow performing NMR structural and RNA-binding studies of ZCCHC9 with the aim to investigate its role in the RNA quality control in human.
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