Publication details
Single-nukleotidové polymorfizmy -426C-T, -384A-G and 67G- A genu pro eotaxin u dospělých pacientů s atopickou dermatitídou
| Title in English | Eotaxin gen -426C-T, -384A-G and 67G-A single-nucleotide polymorphisms and atopic dermatitis in Czech adult AD patients |
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| Authors | |
| Year of publication | 2010 |
| Type | Article in Proceedings |
| Conference | 2. Brněnský dermatologický den Antonína Trýba - Abstrakta, Brno, 15.10.2010 |
| MU Faculty or unit | |
| Citation | |
| Field | Dermatovenerology |
| Keywords | genetic of atopic dermatitis; eotaxin gen |
| Description | Eotaxin may play an important role in atopic dermatitis as a potent immunomodulatory agent. In a pilot study, three single-nucleotide polymorphisms (-426C-T, -384A-G and 67G-A ) of the eotaxin gene were associated wit- some phenotypes of the AD patients. Detection of this polymorphisms seems to be a promising way for finding of clinically valid gene biomarkers for the disease. |