Publication details

Matrix metalloproteinase 8 (MMP8) gene polymorphisms in chronic periodontitis

Authors

IZAKOVIČOVÁ HOLLÁ Lydie HRDLIČKOVÁ Barbara VOKURKA Jan FASSMANN Antonín

Year of publication 2012
Type Article in Periodical
Magazine / Source Arch Oral Biol
MU Faculty or unit

Faculty of Medicine

Citation
Doi http://dx.doi.org/10.1016/j.archoralbio.2011.08.018
Field ORL, ophthalmology, stomatology
Keywords gene polymorphism; MMPs; periodontitis; periodontal pathogen
Description Previous studies have suggested that some functional polymorphisms in the matrix metalloproteinase (MMPs) genes are associated with the risk of periodontal disease. However, to date no study has investigated MMP8 gene variants in relation to chronic periodontitis (CP). The aim of this study was to analyze polymorphisms in the MMP8 gene and their associations with microbial composition and clinical manifestation of CP.
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