Publication details

Využití in vitro biotestů pro hodnocení kontaminace vodního prostředí AhR-aktivními látkami.

Title in English USE OF IN VITRO BIOASSAYS TO EVALUATE CONTAMINATION OF AQUATIC ENVIRONMENT WITH AhR-ACTIVE COMPOUNDS
Authors

MACÍKOVÁ Petra GIESY J. HILSCHEROVÁ Klára

Year of publication 2011
Type Article in Periodical
Magazine / Source Bulletin VÚRH Vodňany
MU Faculty or unit

Faculty of Science

Citation
Field Environment influence on health
Keywords AhR-dependent toxicity; river ecosystem; passive sampling; in vitro assays
Description The aquatic environment is contaminated with many types of chemical compounds that can be dissolved in water or bound to solid particles and in sediments. In complex mixtures is very difficult to estimate their toxic potential. Many types of hydrophobic persistent pollutants are able to activate arylhydrocarbon receptor (AhR) that might have negative consequences for organisms’ health. Suitable tools to assess AhR-active (dioxin-like) compounds in aquatic samples are in vitro bioassays in combination with chemical analysis.
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