RNDr. Michaela Bosáková, Ph.D.

2018

• Regulation of ciliary function by fibroblast growth factor signaling identifies FGFR3-related disorders achondroplasia and thanatophoric dysplasia as ciliopathies

  BOSÁKOVÁ Michaela VAŘECHA Miroslav HAMPL Marek DURAN Ivan NITĂ Alexandru BUCHTOVÁ Marcela DOSEDELOVA Hana MACHÁT Radek XIE Yangli NI Zhenhong MARTIN Jorge H. CHEN Lin JANSEN Gert KRAKOW Deborah KREJČÍ Pavel

  Article in Periodical

  Human molecular genetics, year: 2018, volume: 27, edition: 6, DOI

• The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases

  FAFÍLEK Bohumil BÁLEK Lukáš BOSÁKOVÁ Michaela VAŘECHA Miroslav NITĂ Alexandru GREGOR Tomáš GUDERNOVÁ Iva KŘENOVÁ Jitka GHOSH S. PISKÁČEK Martin JONATOVA Lucie ČERNOHORSKÁ Nicole ZIEBA J.T. KOSTAS M. HAUGSTEN E.M. WESCHE J. ERNEUX C. TRANTÍREK Lukáš KRAKOW D. KREJČÍ Pavel

  Article in Periodical

  SCIENCE SIGNALING, year: 2018, volume: 11, edition: 548, DOI

2017

• An Efficient Method for Generation of Knockout Human Embryonic Stem Cells Using CRISPR/Cas9 System

  BOHAČIAKOVÁ Dáša RENZOVÁ Tereza FEDOROVÁ Veronika BARÁK Martin BOSÁKOVÁ Michaela HAMPL Aleš ČAJÁNEK Lukáš

  Article in Periodical

  Stem Cells and Development, year: 2017, volume: 26, edition: 21, DOI

• ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFR3

  BÁLEK Lukáš GUDERNOVÁ Iva VESELA Iva HAMPL Marek ORALOVÁ Veronika BOSÁKOVÁ Michaela VAŘECHA Miroslav NĚMEC Pavel HALL Terence ABBADESSA Giovanni HATCH Nan BUCHTOVÁ marcela KREJČÍ Pavel

  Article in Periodical

  Bone, year: 2017, volume: 105, edition: DEC 2017, DOI

• Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480

  GUDERNOVÁ Iva BÁLEK Lukáš VAŘECHA Miroslav FIALOVÁ KUČEROVÁ Jana BOSÁKOVÁ Michaela FAFÍLEK Bohumil PALUŠOVÁ Veronika ULDRIJAN Stjepan TRANTÍREK Lukáš KREJČÍ Pavel

  Article in Periodical

  Oncotarget, year: 2017, volume: 8, edition: 65, DOI

• One reporter for in-cell activity profiling of majority of protein kinase oncogenes

  GUDERNOVÁ Iva TRANTÍRKOVÁ Silvie EL GHANNAMOVÁ Barbora FAFÍLEK Bohumil VAŘECHA Miroslav BÁLEK Lukáš HRUBÁ Eva JONÁTOVÁ Lucie JELÍNKOVÁ Iva BOSÁKOVÁ Michaela TRANTÍREK Lukáš MAYER Jiří KREJČÍ Pavel

  Article in Periodical

  eLife, year: 2017, volume: 6, edition: "e21536", DOI

• Properties of Human Embryonic Stem Cells and Their Differentiated Derivatives Depend on Nonhistone DNA-Binding HMGB1 and HMGB2 Proteins

  BAGHERPOOR Alireza Jian DOLEŽALOVÁ Dáša BÁRTA Tomáš KUČÍREK Martin SANI Soodabeh Abbasi EŠNER Milan BOSÁKOVÁ Michaela VINARSKÝ Vladimír PEŠKOVÁ Lucie HAMPL Aleš ŠTROS Michal

  Article in Periodical

  Stem Cells and Development, year: 2017, volume: 26, edition: 5, DOI

• Role of Primary Cilia in Odontogenesis

  HAMPL Marek CELA P. SZABO-ROGERS H.L. BOSÁKOVÁ Michaela DOSEDELOVA H. KREJČÍ Pavel BUCHTOVÁ marcela

  Article in Periodical

  Journal of Dental Research, year: 2017, volume: 96, edition: 9, DOI

• Statins do not inhibit the FGFR signaling in chondrocytes

  FAFÍLEK Bohumil HAMPL Marek ŘIČÁNKOVÁ Nikola VESELA I. BÁLEK Lukáš BOSÁKOVÁ Michaela GUDERNOVÁ Iva VAŘECHA Miroslav BUCHTOVÁ marcela KREJČÍ Pavel

  Article in Periodical

  Osteoarthritis and Cartilage, year: 2017, volume: 25, edition: 9, DOI

• Tyrosine Kinase Expressed in Hepatocellular Carcinoma, TEC, Controls Pluripotency and Early Cell Fate Decisions of Human Pluripotent Stem Cells via Regulation of Fibroblast Growth Factor-2 Secretion

  VÁŇOVÁ Tereza KONEČNÁ Žaneta ZBOŇÁKOVÁ Zuzana LA VENUTA Giuseppe ZOUFALOVÁ Karolína JELÍNKOVÁ Šárka VAŘECHA Miroslav ROTREKL Vladimír KREJČÍ Pavel NICKEL Walter DVOŘÁK Petr BOSÁKOVÁ Michaela

  Article in Periodical

  Stem Cells, year: 2017, volume: 35, edition: 9, DOI