Publication details

Atmospheric Pressure Plasma Polymerized Oxazoline-Based Thin Films-Antibacterial Properties and Cytocompatibility Performance

Authors

SŤAHEL Pavel MAZÁNKOVÁ Věra TOMEČKOVÁ Klára MATOUŠKOVÁ Petra BRABLEC Antonín PROKEŠ Lubomír JURMANOVÁ Jana BURŠÍKOVÁ Vilma PŘIBYL Roman LEHOCKÝ Marián HUMPOLÍČEK Petr OZAITIN Kadir TRUNEC David

Year of publication 2019
Type Article in Periodical
Magazine / Source Polymers
MU Faculty or unit

Faculty of Science

Citation
Web https://www.mdpi.com/2073-4360/11/12/2069
Doi http://dx.doi.org/10.3390/polym11122069
Keywords antibiofouling; plasma polymer; oxazoline
Description Polyoxazolines are a new promising class of polymers for biomedical applications. Antibiofouling polyoxazoline coatings can suppress bacterial colonization of medical devices, which can cause infections to patients. However, the creation of oxazoline-based films using conventional methods is difficult. This study presents a new way to produce plasma polymerized oxazoline-based films with antibiofouling properties and good biocompatibility. The films were created via plasma deposition from 2-methyl-2-oxazoline vapors in nitrogen atmospheric pressure dielectric barrier discharge. Diverse film properties were achieved by increasing the substrate temperature at the deposition. The physical and chemical properties of plasma polymerized polyoxazoline films were studied by SEM, EDX, FTIR, AFM, depth-sensing indentation technique, and surface energy measurement. After tuning of the deposition parameters, films with a capacity to resist bacterial biofilm formation were achieved. Deposited films also promote cell viability.
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