A web-based bioinformatic tool LYNX for targeted LYmphoid NeXt- generation sequencing data analysis and visualization for hematooncology.

• Authors: REIGL Tomáš; PORC Jakub Paweł; NAVRKALOVÁ Veronika; HYNŠT Jakub; PÁL Karol; STRÁNSKÁ Kamila; KOTAŠKOVÁ Jana; POSPÍŠILOVÁ Šárka; PLEVOVÁ Karla
• Year of publication: 2023
• Type: Conference abstract
• MU Faculty or unit: Central European Institute of Technology
• Description: Next-generation sequencing (NGS) is one of the most rapidly expanding technologies in laboratory medicine. In routine diagnostics, a single NGS experiment can replace several laboratory tests and provide more information about the disease being tested. Commonly, the assistance of a qualified bioinformatician or a dedicated tool is necessary for the data analysis. Our team has created an integrative, targeted NGS panel that detects genetic markers common for most abundant lymphoid malignancies (PMID: 34082072). For this panel, we have developed a bioinformatic tool, LYNX, with a user interface (UI) that allows diagnosticians to easily analyze the data and interactively visualize the results. This facilitates data interpretation and speeds up diagnostic procedures.

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