National institute for cancer research (NÚVR)
- Project Identification
- LX22NPO5102
- Project Period
- 6/2022 - 12/2025
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- national recovery plan
- 5.1 EXCELES
- MU Faculty or unit
-
Faculty of Medicine
- prof. RNDr. Ondřej Slabý, Ph.D.
- Bc. Klára Baďurová
- MUDr. Viera Bajčiová, CSc.
- Mgr. Júlia Bohošová, Ph.D.
- Mgr. Michaela Bosáková, Ph.D.
- Mgr. Pavla Bouchalová, Ph.D.
- Ing. Daniel Buša
- Aleksandra Anna Czyrek, PhD
- PharmDr. Martin Čulen, Ph.D.
- prof. MUDr. Michael Doubek, Ph.D.
- Mgr. Bohumil Fafílek, Ph.D.
- Mgr. Zuzana Feketová, Ph.D.
- Mgr. Jan Hýl
- prof. RNDr. Mgr. Marie Jarošová, CSc.
- Mgr. Martina Jelínková
- Mgr. Alena Kopková
- MUDr. Marie Kramárová
- RNDr. Pavel Krejčí, Ph.D.
- MUDr. Zuzana Kuttnerová
- MUDr. Michal Kýr, Ph.D.
- Mgr. Petr Lapčík, Ph.D.
- Mgr. Jana Loskotová
- MUDr. Tomáš Merta
- MUDr. Peter Múdry, Ph.D.
- Mgr. Veronika Navrkalová, Ph.D.
- Hana Novotná
- Mgr. Lukáš Pečinka
- Mgr. Karla Plevová, Ph.D.
- Barbora Podhajská
- Mgr. Petra Pokorná
- Helena Poláková
- MUDr. Kristýna Polášková, Ph.D.
- Mgr. Ing. Jakub Paweł Porc
- Mgr. Vendula Rašková, Ph.D.
- MUDr. Ondřej Rohleder
- Ing. Mgr. Michaela Ručková
- Mgr. Dagmar Smitalová
- Mgr. Bc. Karolína Smolková
- Mgr. Kamila Stránská, Ph.D.
- Ing. Michaela Stroblová, Ph.D.
- Marcela Suránová
- Mgr. Hana Svozilová
- doc. RNDr. Sabina Ševčíková, Ph.D.
- prof. MUDr. Jaroslav Štěrba, Ph.D.
- MUDr. Silvie Šurková
- MUDr. Terézia Tureková
- Dr. Suzanne Dawn Turner
- Mgr. Stjepan Uldrijan, CSc.
- doc. RNDr. Petr Vaňhara, Ph.D.
- Mgr. Marek Večeřa
- MUDr. Klára Vejmělková
- Mgr. Bc. Monika Vlachová
- Mgr. Petra Vychytilová, Ph.D.
- MUDr. Danica Zapletalová, Ph.D.
- Other MU Faculty/Unit
-
Faculty of Science
- prof. Mgr. Vítězslav Bryja, Ph.D.
- Mgr. David Bednář, Ph.D.
- doc. Mgr. Petr Beneš, Ph.D.
- Mgr. Karolína Bořánková
- doc. Mgr. Pavel Bouchal, Ph.D.
- Mgr. Kristína Gömöryová
- Faraneh Haddadi
- RNDr. Vendula Hlaváčková Pospíchalová, Ph.D.
- Mgr. Jana Horáčková
- Mgr. Šárka Hrachovinová
- Mgr. Pavlína Janovská, Ph.D.
- Bc. Aneta Jarošková
- MUDr. Marta Ježová, Ph.D.
- Mgr. Lucia Knopfová, Ph.D.
- Mgr. Jiří Kohoutek, Ph.D.
- Mgr. Marek Kravec, Ph.D.
- Johana Marešová
- Stanislav Mazurenko, PhD
- MUDr. Jan Mičan
- Mgr. Antónia Mikulová
- Mgr. Jarmila Navrátilová, Ph.D.
- Ing. Zuzana Orlová
- Bc. Daniel Pluskal
- Bc. Andrea Rousová
- Mgr. Kamila Říhová
- Mgr. Eva Slabáková, Ph.D.
- Mgr. Stanislava Sladeček, Ph.D.
- Mgr. Karel Souček, Ph.D.
- Ing. Jan Šimoník
- RNDr. Jan Škoda, Ph.D.
- Ing. Jan Velecký
- prof. RNDr. Renata Veselská, Ph.D., M.Sc.
- Mgr. Olga Vondálová Blanářová, Ph.D.
- Other MU Faculty/Unit
-
Central European Institute of Technology
- prof. RNDr. Šárka Pospíšilová, Ph.D.
- Bc. Erika Bajusová
- Mgr. Tereza Deissová
- Mgr. Lenka Dostálová
- Bc. Kryštof Hlaváč
- Mgr. Lenka Humpolíková Adámková, Ph.D.
- Libuše Janská, BA
- Bc. Jana Jedličková
- prof. MUDr. Zdeněk Kala, CSc.
- doc. MUDr. Tomáš Kazda, Ph.D.
- doc. MUDr. Igor Kiss, Ph.D., MBA
- Bc. Filip Kledus
- Mgr. Kateřina Koželková
- Mgr. Adriana Ladungová
- Mgr. Táňa Macháčková, Ph.D.
- Ludmila Marková
- doc. MUDr. Mgr. Marek Mráz, Ph.D.
- Mgr. Karol Pál, Ph.D.
- Mgr. Hana Pálová, Ph.D.
- Mgr. František Siegl
- prof. MUDr. Marek Svoboda, Ph.D.
- doc. Mgr. Jiří Šána, Ph.D.
- Mgr. Michal Šmída, Dr. rer. nat.
- Mgr. Jiří Štika, Ph.D.
- Mgr. Karolína Trachtová
- doc. Mgr. Lukáš Trantírek, Ph.D.
- RNDr. Silvie Trantírková, Ph.D.
- RNDr. Josef Večeřa, Ph.D.
- MVDr. Martina Vodinská
- Keywords
- oncology, cancer, national institute
- Cooperating Organization
-
Institute of Microbiology of the ASCR, v. v. i.
- Responsible person Ing. Jiří Hašek, CSc.
- Responsible person Ing. Miroslava Anděrová, CSc.
- Responsible person Dr. Ing. Jiří Kotek
- Responsible person RNDr. Petr Dráber, DrSc.
- Responsible person prof. RNDr. Jan Konvalinka, CSc.
- Responsible person doc. Ing. Pavel Peterka, Ph.D.
- Responsible person prof. MUDr. Alexi Šedo, DrSc.
- Responsible person prof. MUDr. Martin Procházka, Ph.D.
- Responsible person prof. MUDr. Marek Svoboda, Ph.D.
The aim of the project is to create a nationwide network of collaborating workplaces conducting cutting-edge research in the field of oncology, which will take the form of a "National Institute". The reason for the creation of this authority is that research in oncology is currently not coordinated in any way and is fragmented across institutions.
The establishment of a National Institute for Cancer Research will bring together cutting-edge scientific expertise, tertiary education and relevant medical/health information resources. The thematic complementarity of the individual departments within the National Cancer Research Institute will allow for a comprehensive approach necessary for modern cancer research, concentrating on priority areas of medical education and research in the Czech Republic. Cancer research will thus become much more coordinated, strategic and efficient.
The great advantage of the National Institute is its transformative character, i.e. no new infrastructure will be built (an exception is the necessary construction of the GMP for somatic cell and gene therapy ATMP in pavilion C03), but the development and modernisation of existing capacities and human resources. This approach is highly efficient and financially sustainable in the long term.
The network of collaborating sites will consist of three Nodes (Prague Node - coordinator, Brno Node, Olomouc Node), which will cover the whole Czech Republic. The individual Nodes will be connected through a consortium agreement that defines the frameworks and rules of cooperation.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 51
2023
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Catechol-O-methyl transferase suppresses cell invasion and interplays with MET signaling in estrogen dependent breast cancer
Scientific Reports, year: 2023, volume: 13, edition: 1, DOI
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Daratumumab with lenalidomide and dexamethasone in relapsed or refractory multiple myeloma patients – real world evidence analysis
Annals of Hematology, year: 2023, DOI
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DiaPASEF proteotype analysis indicates changes in cell growth and metabolic switch induced by caspase-9 inhibition in chondrogenic cells
Proteomics, year: 2023, DOI
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Distinct p53 phosphorylation patterns in chroniclymphocytic leukemia patients are reflected in theactivation of circumjacent pathways upon DNA damage
MOLECULAR ONCOLOGY, year: 2023, volume: 17, edition: 1, DOI
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Driver and actionable mutations in younger patients with lung cancer-are we searching properly?
Biomedical Papers, Olomouc: Palacky University, year: 2023, DOI
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Electrochemical biosensors for analysis of DNA point mutations in cancer research
Analytical and Bioanalytical Chemistry, year: 2023, volume: 415, edition: 6, DOI
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Engine shutdown: migrastatic strategies and prevention of metastases
Trends in Cancer, year: 2023, volume: 9, edition: 4, DOI
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FoxP3 Expression in Tumor-Infiltrating Lymphocytes as Potential Predictor of Response to Immune Checkpoint Inhibitors in Patients with Advanced Melanoma and Non-Small Cell Lung Cancer
Cancers, year: 2023, volume: 15, edition: 6, DOI
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Identificationof novel therapeutic options for venetoclax-resistant AML cells through drug repurposing.
Year: 2023, type: Conference abstract
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MicroRNA Profiling of Self-Renewing Human Neural Stem Cells Reveals Novel Sets of Differentially Expressed microRNAs During Neural Differentiation In Vitro
Stem Cell Reviews and Reports, year: 2023, DOI