Publication details
Merging Bambus[6]uril and Biotin[6]uril into an Enantiomerically Pure Monofunctionalized Hybrid Macrocycle
| Authors | |
|---|---|
| Year of publication | 2024 |
| Type | Article in Periodical |
| Magazine / Source | Organic Letters |
| MU Faculty or unit | |
| Citation | |
| Web | https://pubs.acs.org/doi/10.1021/acs.orglett.3c03715 |
| Doi | http://dx.doi.org/10.1021/acs.orglett.3c03715 |
| Keywords | Anions; Carboxyls; Cavities; Macrocycles; Supramolecular chemistry |
| Attached files | |
| Description | Bambus-[6]-urils and biotin[6]-urils are macrocycles with an exceptional affinity for inorganic anions. Here, we investigated statistical condensation of 2,4-dibenzylglycoluril and d-biotin, monomers of the corresponding macrocycles, to prepare the enantiomerically pure macrocycle 1 containing a single d-biotin and five glycoluril units. Host-guest properties of 1 in chloroform solution and solid state were investigated. The macrocycle 1 bearing a single functional group was employed in the formation of [1]-rotaxane utilizing reversible covalent bonds. |
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