Adsorptive Stripping Analysis of DNA with Admittance Detection

• Authors: JELEN František; VETTERL Vladimír; BĚLUŠA Petr; HASOŇ Stanislav
• Year of publication: 2000
• Type: Article in Periodical
• Magazine / Source: Electroanalysis
• MU Faculty or unit: Faculty of Science
• Field: Biophysics
• Keywords: voltammetric analysis; DNA; admittance measurements; DNA damage
• Description: Native, denatured and damaged calf thymus DNA was studied by admittance measurement using hanging mercury drop electrode. The obtained results suggest that in damaged regions of double stranded native DNA the bases are accesible for the interaction with the electrode producing peak 3 without passing through the potential region U around -1.2 V, where double stranded DNA is supposed to be slowly opened.

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