Publication details

Adsorptive Stripping Analysis of DNA with Admittance Detection


JELEN František VETTERL Vladimír BĚLUŠA Petr HASOŇ Stanislav

Year of publication 2000
Type Article in Periodical
Magazine / Source Electroanalysis
MU Faculty or unit

Faculty of Science

Field Biophysics
Keywords voltammetric analysis; DNA; admittance measurements; DNA damage
Description Native, denatured and damaged calf thymus DNA was studied by admittance measurement using hanging mercury drop electrode. The obtained results suggest that in damaged regions of double stranded native DNA the bases are accesible for the interaction with the electrode producing peak 3 without passing through the potential region U around -1.2 V, where double stranded DNA is supposed to be slowly opened.
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