Publication details
Diabetes insipidus, následovaný po 4 letech dysartrií a lehkou pravostrannou hemiparézou - první klinické příznaky Erdheimovy-Chesterovy nemoci. Popis a zobrazení případu s přehledem informací o této nemoci
| Title in English | Diabetes insipidus followed after 4 years dysarthria and light dextral hemiparesis - 1st symptom of Erdheim-Chester's disease. A casuistry. |
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| Authors | |
| Year of publication | 2009 |
| Type | Article in Periodical |
| Magazine / Source | Vnitřní lékařství |
| MU Faculty or unit | |
| Citation | |
| Field | Oncology and hematology |
| Keywords | Diabetes insipidus;Erdheim-Chester's disease; multiple myeloma |
| Description | This casuistry is focused on one pacitent with Erdheim-Chester's disease and with clinical symptom of diabetes insipidus.In 2004, diabetes insipidus was the first clinical sign of Erdheim-Chester disease in our patient. Following introduction of substitution therapy with adiuretin, the patient had no further health complaints for four years until 2008 when he gradually developed dysarthria and, consequently, movement disorder in the form of mild right hemiparesis. The first CNS CT scan (2004) did not reveal any pathology. The first pathological MRI of the brain in 2006 - thickening of pituitary stalk by pathological infiltration to 4-5 mm. During the following year, further infiltrates were detected in the CNS. The number and size of CNS infiltrates increased gradually on MRIs performed repeatedly up to 2008. Erdheim-Chester disease has become suspected based on PET-CT examination at the end of 2008. |
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