Publication details

Occurrence of quaternary benzo[c]phenanthridine alkaloids in Stylophorum lasiocarpum (Oliv.) fedde

Authors

PĚNČÍKOVÁ Kristýna URBANOVÁ Jana TÁBORSKÁ Eva

Year of publication 2012
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Attached files
Description For a long time, quaternary benzo[c]phenanthridine alkaloids (QBAs) are known to exhibit diverse biological effects. A great deal of attention is devoted to the main alkaloids sanguinarine (SA ) and chelerythrine (CHE) and their cytotoxicity and induction of apoptosis. These alkaloids also display important anti-proliferative activities against cancer cell lines and have been discussed as potential cytostatic drugs for cancer treatment. In the last years also the other QBAs have received increased attention and new information regarding their biological activities has been published.
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