Informace o publikaci
The effect of uric acid on homocysteine-induced endothelial dysfunction in bovine aortic endothelial cells.
| Autoři | |
|---|---|
| Rok publikování | 2009 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Neuroendocrinology Letters |
| Citace | |
| www | https://www.ncbi.nlm.nih.gov/pubmed/20027155 |
| Klíčová slova | uric acid, homocysteine, endothelial dysfunction |
| Popis | Elevated plasma uric acid indicates an increased risk of cardiovascular diseases associated with endothelial dysfunction. However, the role of uric acid in the pathogenesis of endothelial dysfunction is still a matter of debate. It is not clear whether uric acid is a real causative risk factor, an inert marker, or even a protective molecule with respect to its antioxidant properties. We have studied the effect of uric acid on intact endothelial cells as well as cells with homocysteine-induced endothelial dysfunction. |