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Epidemiology of plasma cell leukemia in the Czech Republic

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ZAPLETALOVÁ Michaela KREJČÍ Denisa JARKOVSKÝ Jiří MUŽÍK Jan DUŠEK Ladislav POUR Luděk

Druh Článek v odborném periodiku
Časopis / Zdroj Klinická onkologie
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
WWW https://www.linkos.cz/casopis-klinicka-onkologie/2019-02-15-1/epidemiologie-plazmocelularni-leukemie-v-ceske-republice/
Doi http://dx.doi.org/10.14735/amko201947
Klíčová slova plasma cell leukemia; epidemiology; Czech National Cncer Registry; Czech Republic
Popis BACKGROUND: Plasma cell leukemia (PCL) is a rare but most aggressive form of monoclonal gammopathies. PCL is characterized by the presence of clonal plasma cells in peripheral blood. There are two forms of PCL - primary which presents de novo in patients with no evidence of previous multiple myeloma and secondary which is a leukemic transformation of relapsed or refractory disease in patients with previously recognized multiple myeloma. Data from registries such as the CNCR can provide useful information on epidemiology of various dis-eases. These data, however, have several limitations, such as dia-gnostic criteria and proper coding of not only the dis-ease itself, but also its various forms. These limitations have to be taken into account during the process of results interpretation.