Informace o publikaci
Micromechanical cantilever-based biosensors
| Autoři | |
|---|---|
| Rok publikování | 2001 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Sensors and Actuators B Chemical |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Biofyzika |
| Klíčová slova | microcantilever; immunosensor; albumin; immobilization; biosensor |
| Popis | The merging of silicon microfabrication techniques with surface functionalization biochemistry offers new exciting opportunities in developing microscopic biomedical analysis devices with unique characteristics. Micro-mechanical transducers for chemical and biosensing applications represent one possibility. Microcantilevers can transduce a chemical signal into a mechanical motion with high sensitivity. In this review we summarize how cantilever-based sensors can be operated, and their working principle is presented in few selected biosensing experiments which have been performed recently in our groups in the study of biotin-streptavidin and antigen-antibody interactions, and specific surface charge development of organic molecules. We also discuss the advantages of this novel technique as well as its potentials. |
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