Informace o publikaci
Induction of type II iodothyronine 5'-deiodinase and mitochondrial uncoupling protein in brown adipocytes differentiated in cell culture
| Autoři | |
|---|---|
| Rok publikování | 1990 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | FEBS Letters [IF=3.420 (1989); SCI #cit.<8>] |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Genetika a molekulární biologie |
| Klíčová slova | Brown adipose tissue; catecholamine; cell culture; iodothyronine 5'-deiodinase; uncoupling protein |
| Popis | Brown adipocytes differentiated in primary cell culture were found to contain a type II iodothyronine 5'-deiodinase (5'D). Incubation of confluent cells with norepinephrine or dibutyryl-cAMP caused up to 17-fold increase in 5'D activity with a maximum after 8 h. |