Informace o publikaci
Lack of Population Diversity in Human Embryonic Stem-Cell Lines
| Autoři | |
|---|---|
| Rok publikování | 2009 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | New England Journal of Medicine |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Genetika a molekulární biologie |
| Klíčová slova | human embryonic stem cell; population diversity |
| Popis | We determined the genetic ancestry of large collection of stem-cell lines. We have found that widely distributed stem-cell lines lack population diversity and that none of these lines derive from populations with recent African ancestry. Efforts to derive and disseminate new stem-cell lines should now emphasize underrepresented pupulations, to allow researchers to assess the extent to which the ancestry of stem-cell lines influences diesease models, cellular therapies, and drug screening with the use of stem cells. |
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