Informace o publikaci
Direct Voltammetric Analysis of DNA Modified with Enzymatically Incorporated 7-Deazapurines
| Autoři | |
|---|---|
| Rok publikování | 2010 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Analytical Chemistry |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Biofyzika |
| Klíčová slova | 7-deozapurines; voltammetric analysis; carbon electrode |
| Popis | Nucleic acids studies use 7-deazaguanine and 7-deazaadenine as analogues of natural purine bases. We showed that enzymatic incorporation of 7-deazaguanine and 7-deazaadenine can easily be monitored by simple ex situ voltammetric analysis of the modified DNA at carbon electrodes. 7-deazaguanine was shown as an attractive electroactive marker for DNA, efficiently incorporable by PCR. |