Informace o projektu

A rapid robust technique to quantify the invasiveness of cancer cells based on their physical properties

Kód projektu
MUNI/LF-ACC/1180/2022
Období řešení
1/2023 - 12/2024
Investor / Programový rámec / typ projektu
Masarykova univerzita
Fakulta / Pracoviště MU
Lékařská fakulta

A significant number of studies describe that cell deformability is potential important diagnostic predictor of tumor aggressiveness. However, the current cell-deformation-analyzing methods are limited by low robustness or the need for expert operation thus limiting clinical introduction. Still, the advances in quantitative phase imaging (QPI) have made it possible to extract physical parameters from microscopic images of living cells. We demonstrated QPI is valuable just for the detection of cell deformation with much higher robustness and ease of use. In the following, the aim is to test the practical aspects of this experimental conclusion.

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