Informace o publikaci

Cystathionine β-synthase affects organization of cytoskeleton and modulates carcinogenesis in colorectal carcinoma cells

Autoři

LISKOVA Veronika CHOVANCOVA Barbora BABULA Petr REZUCHOVA Ingeborg PAVLOV Kristina Ploth MATUSKOVA Miroslava KRIŽANOVÁ Oľga

Rok publikování 2023
Druh Článek v odborném periodiku
Časopis / Zdroj Frontiers in Oncology
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1178021/full
Doi http://dx.doi.org/10.3389/fonc.2023.1178021
Klíčová slova cystathionine beta-synthase; cytoskeleton; beta-tubulin; colorectal carcinoma cells; xenografts
Popis Background: Cystathionine beta-synthase (CBS), one of three enzymes that endogenously produce hydrogen sulfide, is extensively studied for its relevance in the cells of various tumors. In our previous work, we observed that the immunofluorescence pattern of CBS is very similar to that of tubulin and actin. Therefore, we focused on the potential interaction of CBS with cytoskeletal proteins beta-actin and beta-tubulin and the functional relevance of the potential interaction of these proteins in colorectal carcinoma cell lines.

Používáte starou verzi internetového prohlížeče. Doporučujeme aktualizovat Váš prohlížeč na nejnovější verzi.

Další info