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Interleukin-1 gene variations in post-orthodontic external root resorption

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LINHARTOVÁ Petra ČERNOCHOVÁ Pavlína RAUDENSKÁ Martina LIPKOVÁ Jolana IZAKOVIČOVÁ HOLLÁ Lydie

Rok publikování 2011
Druh Konferenční abstrakty
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Popis External apical root resorption (EARR) is a permanent shortening of the end of the tooth root. EARR is a common clinical complication of orthodontic treatment and is known to occur after trauma and in response to inflammation. Polymorphisms in the interleukin-1 (IL-1) genes play a role in the inflammatory diseases through the modulation of cytokine levels. The aim of this study was to associate two single nucleotide polymorphisms (SNPs) and one variable number of tandem repeats (VNTR) polymorphism in IL-1 with EARR in the Czech population. This study was supported by projects 1M0528 and IGA NT11405-6.
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