Informace o publikaci

Prospective Evaluation of Ultrasound Accuracy in the Detection of Pelvic Carcinomatosis in Patients with Ovarian Cancer

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WEINBERGER Vít FISCHEROVA Daniela SEMERADOVA Ivana SLAMA Jiri DUNDR Pavel DUŠEK Ladislav CIBULA David ZIKAN Michal

Rok publikování 2016
Druh Článek v odborném periodiku
Časopis / Zdroj Ultrasound in Medicine and Biology
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Doi http://dx.doi.org/10.1016/j.ultrasmedbio.2016.05.014
Obor Onkologie a hematologie
Klíčová slova Carcinomatosis; Diagnosis; Ovarian cancer; Peritoneum; Prospective studies; Ultrasonography
Popis We analyzed the accuracy of transvaginal sonography in detection of pelvic carcinomatosis in ovarian cancer patients and factors (age, body mass index, performance status, ascites, stage, histotype, tumor grade) influencing the performance of ultrasound. In this prospective study, all 191 consecutively included patients underwent a pre-operative ultrasound staging examination according to institutional protocol. Peritoneal spread was assessed on the basis of peri-operative findings or histology. The area under the receiver operating characteristic curve for the detection of carcinomatosis was 0.90 (0.84-0.93); the sensitivity was 84% (95% confidence interval [CI]: 75%-%90), specificity 96% (95% CI: 89%-99%), positive predictive value 96% (95% CI: 89%-99%), negative predictive value 83% (95% CI: 74%-90%) and overall accuracy 89% (95% CI: 84%-93%). We report that transvaginal sonography is clinically useful in the detection of pelvic carcinomatosis.

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