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Western blot determination of IgG avidity in primary and secondary syphilis.

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WOZNICOVÁ Vladana VOTAVA Miroslav

Rok publikování 2001
Druh Článek v odborném periodiku
Časopis / Zdroj Scripta medica (Brno)
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Obor Mikrobiologie, virologie
Klíčová slova low-avidity IgG; syphilis; Western blot
Popis IgG avidity to p15.5 kD, p17 kD, and p47 kD antigens of Treponema pallidum was analysed by a new avidity assay termed avidity Western blot. Group I consisted of sera from 27 patients with primary and secondary syphilis, group II comprised 10 subjects with latent syphilis. Low-avidity antibodies were directed against the p17 kD and p47 kD antigens in group I and against the p47 kD antigen in group II. No low-avidity IgG antibodies were detected by ELISA, a routine method for avidity assessment.

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