Mgr. Jiřina Procházková, Ph.D.

Curriculum Vitae

Person-Related Identification Information

• Jiřina Procházková, MSc., PhD
• roz. Zatloukalová, červen 1981, okr. Šumperk

Department

• Preclinical Centre of Masaryk University

Employment - Position

• Researcher

Education and Academic Qualifications

• 2004: MSc.- Molecular Biology and Genetics, Masaryk Universitry, Brno
• 2008: PhD. - Animal physiology, Masaryk University, Brno

Employment

• 2005-2021: Veterinary Research Institute - PhD student, Researcher
• 2006-2025: Institute of Biophysics - PhD student, postdoc, Researcher
• (2011-2016: career break- Maternity leave)
• 2012-2014: Masaryk University - Technology specialist
• 2025-now: Masaryk University - Infrastructure coordinator, Researcher

Teaching Activities

• Bi6871 Health Risks
• Bi6726 Molecular Toxicology

Scientific and Research Activities

• cancer progression, sphingolipidomics, extracellular vesicles, intercellular communication, molecular toxicology

Internship

• September 2019 / Universidade do Porto, Porto, Portugal

University Activities

• -

Awards Related to Science and Research

• 2024 / IBP CAS Award for best methodology - J Lipid Res 65(9): 100609
• 2023 / IBP CAS - Program of internal support for Junior Scientists Single-cell profiling of surface glycosphingolipids opens a new dimension for deconvolution of breast cancer intratumoral heterogeneity and phenotypic plasticity
• 2008 / IBP CAS IBP award for Young scientists
• 2006 - Program rektora Masarykovy Univerzity Brno pro podporu vynikajících disertačních prací Vydavatel: MUNI · květen 2006

Major Publications

• PROCHÁZKOVÁ, Jiřina; Zuzana KAHOUNOVA; Jan VONDRÁČEK a Karel SOUČEK. Aryl hydrocarbon receptor as a drug target in advanced prostate cancer therapy - obstacles and perspectives. TRANSCRIPTION-AUSTIN. UNITED STATES: TAYLOR & FRANCIS INC, 2024, 20 s. ISSN 2154-1264. Dostupné z: https://doi.org/10.1080/21541264.2024.2334106. info
• HYZDALOVA, Martina; Jiřina PROCHÁZKOVÁ; Nicol STRAKOVA; Katerina PENCIKOVA; Simona STRAPÁČOVÁ; Jana SLOVÁČKOVÁ; Simona KAJABOVA; Helena LIBALOVA; Jan TOPINKA; Markéta KABÁTKOVÁ; Jan VONDRÁČEK; Steen MOLLERUP a Miroslav MACHALA. Transcriptional and phenotypical alterations associated with a gradual benzo[a]pyrene-induced transition of human bronchial epithelial cells into mesenchymal-like cells. Environmental Toxicology and Pharmacology. Amsterdam: Elsevier Science B.V., 2024, roč. 107, 13 s. ISSN 1382-6689. Dostupné z: https://doi.org/10.1016/j.etap.2024.104424. info
• PROCHÁZKOVÁ, Jiřina; Radek FEDR; Barbora HRADILOVÁ; Barbora KVOKAČKOVÁ; Josef SLAVIK; Ondrej KOVAC; Miroslav MACHALA; Pavel FABIAN; Jiri NAVRATIL; Simona KRACALIKOVA; Monika LEVKOVA; Petra OVESNÁ; Jan BOUCHAL a Karel SOUČEK. Single-cell profiling of surface glycosphingolipids opens a new dimension for deconvolution of breast cancer intratumoral heterogeneity and phenotypic plasticity. JOURNAL OF LIPID RESEARCH. AMSTERDAM: ELSEVIER, 2024, roč. 65, č. 9, s. 1-15. ISSN 0022-2275. Dostupné z: https://doi.org/10.1016/j.jlr.2024.100609. URL info
• HYZDALOVA, Martina; Jiřina PROCHÁZKOVÁ; Simona STRAPACOVA; Lucie SVRZKOVA; Ondřej VACEK; Radek FEDR; Zdeněk ANDRYSÍK; Eva HRUBA; Helena LIBALOVA; Jiri KLEMA; Jan TOPINKA; Josef MASEK; Karel SOUČEK; Jan VONDRÁČEK a Miroslav MACHALA. A prolonged exposure of human lung carcinoma epithelial cells to benzo[a]pyrene induces p21-dependent epithelial-to-mesenchymal transition (EMT)-like phenotype. Chemosphere. Oxford: Pergamon-Elsevier Science Ltd, 2021, roč. 263, January 2021, s. 1-15. ISSN 0045-6535. Dostupné z: https://doi.org/10.1016/j.chemosphere.2020.128126. URL info
• MACHALA, Miroslav; Josef SLAVIK; Ondrej KOVAC; Jiřina PROCHÁZKOVÁ; Katerina PENCIKOVA; Martina PARENICOVA; Nicol STRAKOVA; Jan KOTOUCEK; Pavel KULICH; Steen MOLLERUP; Jan VONDRÁČEK a Martina HYZDALOVA. Changes in Sphingolipid Profile of Benzo[a]pyrene-Transformed Human Bronchial Epithelial Cells Are Reflected in the Altered Composition of Sphingolipids in Their Exosomes. International Journal of Molecular Sciences. Basel: Multidisciplinary Digital Publishing Institute, 2021, roč. 22, č. 17, 17 s. ISSN 1422-0067. Dostupné z: https://doi.org/10.3390/ijms22179195. info
• SLOVACKOVA, Jana; Josef SLAVIK; Pavel KULICH; Josef VECERA; Ondrej KOVAC; Hana PACULOVA; Nicol STRAKOVA; Radek FEDR; Joao Pedro SILVA; Felix CARVALHO; Miroslav MACHALA a Jiřina PROCHÁZKOVÁ. Polychlorinated environmental toxicants affect sphingolipid metabolism during neurogenesis <i>in vitro</i>. Toxicology. Clare, Ireland: Elsevier Sci Ireland Ltd, 2021, roč. 463, 12 s. ISSN 0300-483X. Dostupné z: https://doi.org/10.1016/j.tox.2021.152986. info
• VEČEŘA, Josef; Jiřina PROCHÁZKOVÁ; Veronika ŠUMBEROVÁ; Veronika PÁNSKÁ; Hana PACULOVÁ; Martina KOHUTKOVÁ LÁNOVÁ; Jan MAŠEK; Dáša BOHAČIAKOVÁ; Emma Rachel ANDERSSON a Jiří PACHERNÍK. Hypoxia/Hif1 Alpha prevents premature neuronal differentiation of neural stem cells through the activation of Hes1. Stem Cell Research. Amsterdam: Elsevier, 2020, roč. 45, May 2020, s. 1-11. ISSN 1873-5061. Dostupné z: https://doi.org/10.1016/j.scr.2020.101770. URL info
• PROCHÁZKOVÁ, Jiřina; Josef SLAVIK; Jan BOUCHAL; Monika LEVKOVA; Zlata HUSKOVA; Jiri EHRMANN; Petra OVESNÁ; Zdenek KOLAR; Pavel SKALICKY; Nicol STRAKOVA; Ondrej ZAPLETAL; Alois KOZUBÍK; Jiřina HOFMANOVÁ; Jan VONDRÁČEK a Miroslav MACHALA. Specific alterations of sphingolipid metabolism identified in EpCAM-positive cells isolated from human colon tumors. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. AMSTERDAM: ELSEVIER, 2020, roč. 1865, č. 9, s. 1-11. ISSN 1388-1981. Dostupné z: https://doi.org/10.1016/j.bbalip.2020.158742. URL info
• PROCHÁZKOVÁ, Jiřina; Simona STRAPÁČOVÁ; Lucie SVRŽKOVÁ; Zdeněk ANDRYSÍK; Martina HYZDALOVA; Eva HRUBÁ; Kateřina PĚNČÍKOVÁ; H LIBALOVA; J TOPINKA; Jiří KLÉMA; JM ESPINOSA; Jan VONDRÁČEK a Miroslav MACHALA. Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands. Toxicology Letters. CLARE: Elsevier, 2018, roč. 292, s. 162-174. ISSN 0378-4274. Dostupné z: https://doi.org/10.1016/j.toxlet.2018.04.024. URL info
• BINÓ, Lucia; Jiřina PROCHÁZKOVÁ; Katarzyna Anna RADASZKIEWICZ; Jan KUČERA; Jana KUDOVÁ; Jiří PACHERNÍK a Lukáš KUBALA. Hypoxia favors myosin heavy chain beta gene expression in an Hif-1alpha-dependent manner. Oncotarget. New York: Impact Journals, 2017, roč. 8, č. 48, s. 83684-83697. ISSN 1949-2553. Dostupné z: https://doi.org/10.18632/oncotarget.19016. URL, URL info
• PROCHÁZKOVÁ, Jiřina; M HYZDALOVA; Simona STRAPÁČOVÁ; Lucie SVRŽKOVÁ; E HRUBA; Josef MAŠEK; H LIBALOVA; Jiří KLÉMA; J TOPINKA; Jan VONDRÁČEK a Miroslav MACHALA. Global changes in expression and functional profile of lung adenocarcinoma cells exposed to various toxic AhR ligands. Toxicology Letters. CLARE: Elsevier, 2017, roč. 280, s. "S85", 1 s. ISSN 0378-4274. Dostupné z: https://doi.org/10.1016/j.toxlet.2017.07.234. URL info
• KUDOVÁ, Jana; Jiřina PROCHÁZKOVÁ; Ondřej VAŠIČEK; Tomáš PEREČKO; Miroslava SEDLÁČKOVÁ; Martin PEŠL; Jiří PACHERNÍK a Lukáš KUBALA. HIF-1alpha Deficiency Attenuates the Cardiomyogenesis of Mouse Embryonic Stem Cells. Plos one. San Francisco: Public Library of Science, 2016, roč. 11, č. 6, s. 1-17. ISSN 1932-6203. Dostupné z: https://doi.org/10.1371/journal.pone.0158358. info
• ŠTEFKOVÁ, Kateřina; Jiřina PROCHÁZKOVÁ a Jiří PACHERNÍK. Alkaline phosphatase in stem cells. Stem Cells International. New York: Hindawi Publishing Corporation, 2015, roč. 2015, č. 02, s. "nestrankovano", 11 s. ISSN 1687-966X. Dostupné z: https://doi.org/10.1155/2015/628368. URL info
• PROCHÁZKOVÁ, Jiřina; Markéta KABÁTKOVÁ; Lenka ŠMERDOVÁ; Jiří PACHERNÍK; Dominika SÝKOROVÁ; Jiří KOHOUTEK; Pavlina SIMECKOVA; Eva HRUBÁ; Alois KOZUBÍK; Miroslav MACHALA a Jan VONDRÁČEK. Aryl Hydrocarbon Receptor Negatively Regulates Expression of the Plakoglobin Gene (Jup). Toxicological sciences. OXFORD: OXFORD UNIV PRESS, 2013, roč. 134, č. 2, s. 258-270. ISSN 1096-6080. Dostupné z: https://doi.org/10.1093/toxsci/kft110. info

2025/12/25