Mathematical modeling of very and ultra-fast oscillations in EEG signals (ModelingUFOs)

This interdisciplinary project on modeling EEG signals links knowledge of the Research and Modeling Team of Nonlinear Dynamics from the Department of Mathematics and Statistics, Faculty of Science, Masaryk University, The First Department of Neurology and CEITEC, Faculty of Medicine, Masaryk University in collaboration with Institute of Scientific Instruments of the CAS. According to recent findings, synchronized very high-frequency oscillations (vHFOs) and ultra-fast oscillations (UFOs) in neural mass measured as an EEG signal are related to focal epilepsy. A model simulating analogous dynamics in neural mass using the latest approaches offered by nonlinear dynamics, bifurcation theory, as well as modern data-driven approaches to infer dynamics from time series, may advance the diagnostic possibilities of focal epilepsy and seizure detection and possibly contribute to the understanding of the origin of the neurological disorder.