Informace o publikaci
LC-MS analysis of chosen phosphatidylcholines in human plasma
| Název česky | LC-MS analýza vybraných fosfatidylcholinů v lidské plazmě |
|---|---|
| Autoři | |
| Rok publikování | 2015 |
| Druh | Konferenční abstrakty |
| Fakulta / Pracoviště MU | |
| Citace | |
| Popis | Phosphatidylcholines (PCs) were studied as potential biomarkers of Alzheimer’s disease by high performance liquid chromatography coupled to mass spectrometry (HPLC MS). PCs were extracted from human plasma, separated by HPLC using several chromatographic columns, mobile phases and gradients. Detection was performed by various MS techniques while the final analyses were provided by quadrupole ion trap. Additionally, phosphatidylcholines were quantified by the standard addition technique and the extraction recoveries and matrix effect of plasma were calculated. |