Informace o publikaci
COMPUTATIONAL MOLECULAR EVOLUTION FROM MATHEMATICAL MODELS TO NOVEL DISTANCE METRICS BASED ON INTRA-GROUP ANALYSIS
| Autoři | |
|---|---|
| Rok publikování | 2011 |
| Druh | Článek ve sborníku |
| Konference | Electronic Devices and Systems IMAPS CS International Conference |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Botanika |
| Klíčová slova | phylogeny; intra-group analysis; substitution model; Markov chains |
| Popis | In the proposed paper we analyse and discuss the molecular evolution from the point of view of mathematical analysis and statistics. Some characteristics of distance-based algorithms for phylogenetic inference are depicted. We furthermore use knowledge of mathematical models to design a modified algorithm for phylogenetic tree reconstruction. We implement the presented methods in the form of a simple phylogenetic library, briefly report about results of our case study and finally show a way for building a web interface for biological purposes through Mobyle portal. Finally, we draw a conclusion and discuss possible future work on the project. |